Author

Dan Cao

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Review Open access Jul 2026

Dynamic tumor microenvironment remodeling in cancer therapy resistance: molecular mechanisms and translational opportunities

Current insights into the molecular mechanisms underlying TME remodeling are summarized, including ECM mechanotransduction, hypoxia-driven signaling, hypoxia-driven signaling, epigenetic regulation, metabolic reprogramming, and extracellular vesicle-mediated communication.

Xiaoying Li, Shuang Dai, Dan Cao et al. · Frontiers in Cell and Develo... · 0 citations