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Review Open access Oct 2026

Synergistic Regulation of Biomaterials and Macrophages: A Novel Paradigm in Immunotherapy

Macrophages have emerged as central regulators of tissue homeostasis, inflammation, and regeneration, yet their remarkable phenotypic plasticity and functional heterogeneity pose substantial challenges for therapeutic modulation. This review provides a comprehensive synthesis of macrophage immunobiology and its trans...

Jia-Yu Zhang, Song-Hang Xing, Shan-Shan Zhang et al. · 0 citations
Review Open access Oct 2026

Innate immune cells in tumor immunity: dual roles, mechanistic insights, and therapeutic opportunities

The tumor microenvironment (TME) is a complex ecosystem that dynamically regulates tumor progression and therapeutic responses. Within this environment, innate immune cells play prominent dual roles, acting as both critical mediators of anti-tumor surveillance and facilitators of tumor immune escape. This review compre...

Song-Hang Xing, Jia-Yu Zhang, Shuang Wang et al. · 0 citations

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