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Open access Sep 2026

Targeted dual-responsive nanocapsules for synergistic cisplatin and paclitaxel prodrug delivery in the treatment of lung cancer

Background The clinical application of traditional chemotherapy for treating patients with lung cancer is restricted by its poor targeting efficacy and severe systemic toxicity. In this study, we developed an acid-sensitive lipid-polymer nanocapsule (PTX/Pt@RGD) for the co-delivery of a redox-sensitive paclitaxel (PTX)...

Xin-Yue Wang, Dan Qin, Chun-Yu Yao et al. · 0 citations
Aug 2026

Electrochemical ultrasensitive detection of miRNA-21 via enzyme-free ROMP amplification.

BACKGROUND The early and accurate detection of miRNA-21 is of great significance for both lung cancer diagnosis and livestock health monitoring, given its conserved sequence across mammals. Herein, we report an enzyme-free electrochemical biosensor based on surface-initiated ring-opening metathesis polymerization (ROMP...

Dan Qin, Shi-Jin Zhou, D. Tsendjav et al. · 0 citations

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