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Open access Aug 2026

MIF-mediated intercellular crosstalk drives antigen-presenting-like cancer-associated fibroblast differentiation in triple-negative breast cancer via TGF-β signaling

Background Triple-negative breast cancer (TNBC) is characterized by an aggressive tumor microenvironment (TME) in which cancer-associated fibroblasts (CAFs) play a pivotal role. However, the molecular mechanisms governing the transformation of quiescent fibroblasts into distinct CAF subtypes within TNBC remain poorly u...

Jun Wang, Ye Li, Jia Zhu et al. · 0 citations

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