Review
Oct 2026
From biomarkers to therapeutic targets: Biomaterial-mediated cfDNA scavenging in inflammation.
Cell-free DNA (cfDNA) displays disease-dependent changes in abundance, fragmentation, composition, and tissue origin. Beyond serving as a noninvasive biomarker, persistent cfDNA can act as a damage-associated molecular pattern, activating TLR9, cGAS-STING, inflammasome signaling, and thromboinflammation. This review sy...
Shi-Bo Liu, Xu Cheng, Lin-Yi Liu et al.
· Biomaterials · 0 citations