Dan Wang

Stage-dependent signaling networks and therapeutic strategies in diabetic retinopathy: from neurovascular dysfunction to angiogenesis and fibrosis

Mechanistically Informed Open-World Enzyme Retrieval with a Dual-Tower Graph-Sequence Model.

Identifying enzymes capable of catalyzing specific chemical transformations across large sequence databases remains a major challenge in biocatalyst discovery. Conventional fingerprint-based methods capture global molecular structure but fail to represent bond-breaking and bond-forming events, limiting generalization t...