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Review Open access Sep 2026

Early recognition and risk stratification of cardiac rupture after acute myocardial infarction: from clinical red flags to emerging biomarkers

Cardiac rupture (CR) remains among the most lethal mechanical complications of acute myocardial infarction (AMI), with in-hospital mortality exceeding 50%. Although primary percutaneous coronary intervention has reduced CR incidence to 1%–2%, mortality has not declined proportionally because the abrupt onset of rupture...

Dan Zhang, Jing Chen, Xiao-Su Wang et al. · 0 citations

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