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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Dan Zhang

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2 papers indexed here

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Review Open access Sep 2026

Daraxonrasib and the era of pan-RAS inhibition: mechanisms, clinical advances, and resistance landscapes

This review synthesizes preclinical and clinical evidence on daraxonrasib and related RAS(ON) inhibitors across RAS-mutant malignancies and provides a comprehensive framework for understanding the promise and challenges of pan-RAS inhibition in precision oncology.

Jiacheng Lou, Dan Zhang · 0 citations
Review Open access Aug 2026

Protein farnesylation: from molecular mechanisms to therapeutic targeting in cancer, aging, and beyond

Protein farnesylation, catalyzed by farnesyltransferase (FTase), covalently attaches a 15-carbon farnesyl lipid to cysteine residues within C-terminal CaaX motifs. This modification governs the subcellular localization, protein–protein interactions, and activity of diverse eukaryotic proteins, including Ras GTPases, nu...

Jiacheng Lou, Dan Zhang, Ying-Jie Wang · 0 citations

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