Second-trimester PM2.5 and PM10 exposure is associated with neonatal metabolome alterations and elevated risk of pregnancy loss: a large-scale matched cohort study with metabolomic profiling.
Prenatal air pollution has been linked to pregnancy loss, but the critical windows and underlying mechanisms remain uncertain. In a propensity score-matched cohort of 30,654 singletons (106 losses, 30,548 live births), we assessed seven exposure windows from pre-pregnancy to peripartum, built a metabolic risk score fro...