Translesion synthesis protein ImuA from Mycolicibacterium smegmatis is a hexameric helicase-nuclease
Translesion DNA synthesis (TLS) enables DNA replication across damaged DNA and promotes stress-induced mutagenesis that contributes to antibiotic resistance in bacteria. The conserved ImuABC mutasome is essential for TLS in many bacterial species, yet the molecular function of its accessory protein, ImuA, has remained...