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Author

Daniel Alberto Madrid González

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Review Open access Sep 2026

Pharmacogenomics in Emergency Care: Actionable Genetic Variability, Drug-Related Toxicity, and Precision Prescribing

Pharmacogenomic variability represents an increasingly relevant determinant of therapeutic response, drug toxicity, and treatment failure in emergency and internal medicine. This study analyzed the clinical applicability of actionable gene–drug interactions associated with acute pharmacological decision-making, severe...

Dayanna Estefania Fernández Astudillo, Cristian David Castro Hernandez, María Alejandra Galindo Van Strahlen et al. · 0 citations
Review Open access Aug 2026

Retinal Vascular Biomarkers for Neurovascular and Multiorgan Risk Assessment: From Fundus Imaging to Predictive Oculomics

Retinal imaging may complement conventional vascular-risk assessment by identifying high-risk phenotypes and supporting targeted systemic evaluation, but it should not replace neuroimaging or specialized cardiovascular, neurological, or renal assessment.

Adrian Jhair Flores Equilea, Natalia Restrepo Hinestrosa, Juan José Parra Serpa et al. · 0 citations
Review Open access Jul 2026

Human Physiology in Deep Space: Cardiovascular and Metabolic Adaptation to Long-Duration Spaceflight

Findings indicate that long-duration spaceflight should be understood as an integrated physiological challenge requiring longitudinal and individualized monitoring, and that future lunar, Martian, and deep-space missions will require combined cardiovascular, metabolic, musculoskeletal, and systemic countermeasures.

Jorge Angel Velasco Espinal, Alexa Fernanda Uriostegui Navarro, Anthony Jesús Pastrana Villares et al. · 0 citations
Review Open access Jul 2026

Photon-Counting Computed Tomography in the Era of Precision Medicine: Technological Advances, Artificial Intelligence Integration, and Multidisciplinary Clinical Applications

The available evidence supports Photon-Counting Computed Tomography as a transformative technology with the potential to redefine diagnostic imaging and strengthen the development of precision medicine across diverse healthcare systems.

A. F. Ortega, Eileen Julliette Orantes Zacaríaz, M. B. Apráez et al. · 0 citations
Review Open access Jul 2026

Immunosenescence in Autoimmune Rheumatic Diseases: Mechanisms, Clinical Consequences, Biomarkers, and Emerging Therapeutic Strategies

Overall, immune senescence should be recognized as a fundamental component of autoimmune rheumatic diseases, providing important opportunities for improving diagnosis, risk stratification, therapeutic decision-making, and long-term clinical outcomes in aging populations.

Benitez Barrios Sosimo Isaac, Gerardo Amaya Villagran, Nemesis Alhelí Pineda Alfaro et al. · 0 citations

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