Daniel B. Graham

Population-scale immune multiome atlas reveals regulatory disease mechanisms.

PepGen: conditional generation of peptides for MHC binding

PepGen provides scalable, motif-constrained MHC II peptide redesign and de novo generation, validated through thorough benchmarks and functional assays.

Peptide-HLA II interaction prediction for post-translationally modified peptides

PepChem, a deep learning model utilizing novel, molecular-level peptide representations that enable predictions for sidechain modifications, bridges the critical gap in PTM-aware immune recognition prediction, with immediate applications in autoimmunity, cancer, and infectious disease.