Author

Daniel B. Haack

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Open access Aug 2026

De novo design of RNA pseudoknots with deep learning.

It is shown that intricate RNA structures can be generated with current deep learning tools through accurate de novo design of pseudoknot secondary structures, suggesting that some difficult RNA design tasks may be tractable without first solving RNA 3D structure prediction.

J. Townley, W. Kladwang, David Baker et al. · Science · 1 citation

Open access Aug 2026

Cryo-EM of a nucleotide-polymerizing ribozyme enables its predictive improvement

Results suggest that accelerating RNA structure determination may speed progress toward nucleotide-based self-replication and suggest that accelerating RNA structure determination may speed progress toward nucleotide-based self-replication.

Deni Szokoli, J. Hingey, V. Wu et al. · bioRxiv · 1 citation