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Author

Daniel J. Puleston

2 papers indexed here

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Open access Jul 2026

T cell differentiation drives programs of resistance to PD-1-mediated inhibition 2260353

Research into basic PD-1 biology, together with the clinical picture of cancer patients treated with PD-1 blockade, converge to emphasize that PD-1 engages complex signaling networks to support T cell homeostasis, differentiation and immune responses. However, there is a lack of comprehensive understanding in the...

Subhasree Sridhar, Woo-Seung Lee, E. Kanshin et al. · 0 citations
Open access Jul 2026

Cellular hallmarks and aging clock of the human lung parenchyma

Multiple cellular hallmarks of lung aging in human tissue are uncovered at single-cell and spatial resolution, including altered alveolar stemness, immune signaling, and macrophage respiration pathways, that may help assess lung biological age and disease risk.

Ke Xu, Grace S. Kim, A. Bhagwat et al. · 0 citations

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