Cross-platform, multi-cohort identification of a caries microbial signature
Abstract Objective To identify a robust salivary microbial signature associated with caries using a cross-platform, multi-cohort design. Design Full-length 16S rRNA gene sequencing (ONT) and shotgun metagenomics (MET) were performed in a derivation cohort with matched data (n = 463). Associations between the oral micro...