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Author

Daniel L. Hurdiss

Utrecht University

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Open access Sep 2026

Integrative structure of norovirus NS3 suggests a role in RNA transport

A full-length, membrane-associated model supports a role for NS3 as a candidate membrane-spanning RNA translocase that may couple ATP hydrolysis to genome movement and establishes a basis for mechanistic studies and structure-guided antiviral design.

Meryl Haas, T. Hoeksma, J. Mills et al. · 0 citations
Open access Aug 2026

Spike and host glycan determinants of HKU1 airway tropism

It is shown that spikes from both serotypes of HKU1 preferentially bind 9-O-acetylated α2,8-linked disialosides, and molecular dynamics simulations indicated that membrane-embedded GT3, but not GD3, presents its glycan chain in a geometry compatible with S1A-mediated engagement.

Robert Creutznacher, Louisa Elizabeth Wallace, Oliver J. Debski-Antoniak et al. · 0 citations

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