Author

Daniel T. Utzschneider

2 papers indexed here

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Open access Sep 2026

In vivo effect of anti-PD-1 on HIV-specific CD8+T-cells in men with HIV

One approach to achieve a cure for HIV infection or allow for people with HIV to safely stop antiretroviral therapy is to enhance HIV-specific immune function by reversing immune exhaustion. Immune checkpoint blockade with anti-PD1 can enhance virus-specific T-cell function ex vivo and in animal models but the effects...

Céline Gubser, Lakshmi Rajdev, Chris Y. Chiu et al. · Nature Communications · 0 citations

Review Open access Jul 2026

Targeting the fate of exhausted CD8+ T cells.

This emerging view frames exhaustion as a context-dependent extension of the memory program rather than its collapse, and highlights how these insights can inform new approaches to manipulate T cell fate for therapeutic benefit.

Daniel T. Utzschneider, Stephen J. Turner · Trends in immunology · 0 citations