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Daniela A. Malide

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Open access Sep 2026

Remodeling of cholesterol metabolism in melanoma progression regulates nuclear membrane mechanics

It is shown that melanoma progression is associated with broad transcriptional remodeling of cholesterol homeostasis that is established early in disease progression, with altered expression of cholesterol biosynthesis genes associated with reduced patient survival.

Michelle A. Baird, Daniela A. Malide, Christian A. Combs et al. · 0 citations

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