Open access
2026
In Silico Screening of Philippine Fabaceae-Derived Phenolic Acids as Potential NAGZ (Β-Hexosaminidase) Inhibitors of Neisseria Gonorrhoeae (PDB ID: 6JTJ)
Phenolic acids from Philippine Fabaceae plants were evaluated as potential inhibitors of the NagZ protein, an enzyme essential for bacterial cell wall recycling and survival, and ellagic acid, 3,4-Di-O-caffeoylquinic acid, and 4-caffeoylquinic acid showed the strongest binding and favorable pharmacokinetic properties.
Grazel Ann M. Caspillo, Sittie Almiraizah A. Masukat, Cristylou Hearth P. Paladin et al.
· International journal of res... · 0 citations