Danielle L. Rudler

TagGen: High-Performance Barcode Generator and Demultiplexer for High-Throughput and Long-Read Sequencing Applications

Background Long-read sequencing platforms, particularly Oxford Nanopore Technologies (ONT), have transformed transcriptomics through direct RNA sequencing. However, their higher error rates – dominated by insertions and deletions – demand longer, more robust sequence barcodes. Existing barcode generation tools suffer...