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Author

Danielle Mantin

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Open access Aug 2026

Evaluation of Phytocannabinoids as Antitumor Agents against Ovarian Cancer Cells in Combination with Carboplatin

Ovarian cancer is the second leading cause of death from gynecologic malignancy worldwide. The integration of phytocannabinoids into oncological care has outpaced our mechanistic understanding of their interactions with frontline chemotherapeutics. In this study, we provide a detailed pharmacological evaluation of two...

Uri Warter, Y. Yogev, D. Nwobodo et al. · 0 citations
Open access Aug 2026

CA-IV-directed small-molecule shuttle enables targeted brain delivery of biologics.

The blood-brain barrier (BBB) presents a challenge for central nervous system (CNS) therapies. Receptor-mediated transcytosis offers a solution, but existing receptor targets are ubiquitous across CNS and peripheral tissues, causing unintended exposure. We identified carbonic anhydrase IV (CA-IV) as a brain-enriched re...

Xiaozhe Ding, Xinhong Chen, Philip Boehm et al. · 0 citations

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