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Author

Daofeng Li

2 papers indexed here

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Open access Jun 2026

Unlocking cis-regulatory landscapes across 500 million years of evolution and disease mechanisms

Abstract Genomic DNA encodes regulatory information that determines where, when, and to what extent genes are expressed. Theoretically, we should be able to identify these transcriptional “instructions” by examining genomic DNA sequence alone, yet this has remained challenging. Here we present the Vertebrate Regulatory...

Tássia Mangetti Gonçalves, Casey L. Stewart, Samantha D. Baxley et al. · 0 citations
Open access Jul 2026

HPRC2: A human pangenome reference with near-complete coverage of common genetic variation

A pangenome reference overcomes the inherent limitation of any individual reference genome by integrating the variation present in a population. We present the Human Pangenome Reference Consortium’s (HPRC) Release 2 (HPRC2), an openly available, second phase pangenome that is an approximately fivefold expansion in geno...

Julian K. Lucas, Prajna Hebbar, Wen-Wei Liao et al. · 1 citation

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