Review
Open access
Aug 2026
Autologous immune system reset for kidney allograft acceptance: mechanisms, evidence, and a testable reconstitution-window model
Autologous hematopoietic stem cell transplantation (AHSCT)-based immune system reset (ISR) is conceptually distinct from donor-hematopoietic chimerism: recipient immunity is deeply depleted and rebuilt from recipient-derived hematopoietic stem/progenitor cells, without intended donor hematopoiesis. This review evaluate...
Chunhui Lyu, Zhishui Chen, Daqiang Zhao
· Frontiers in Medicine · 0 citations