Author

Dario Bizzotto

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Open access Aug 2026

Peripheral neuropathy in a mouse model lacking GBA1 in Schwann cells.

Results indicate a novel role for GBA1 in guaranteeing SC lysosomal function as relevant for peripheral nerve homeostasis and show that decreased degradation efficiency and/or accumulation of bioactive lipids in SCs lacking β-glucocerebrosidase sustain the activation of a repair-SC program, leading to myelin and axonal...

Loris Russo, Ilaria Gregorio, S. Negro et al. · Neurobiology of Disease · 0 citations