Author

Dario Guglietta

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Open access Aug 2026

46 Anti-tumour immune responses in melanoma brain metastases require cDC1 population and the extracranial tumour

It is hypothesize that extracranial tumour inhibits intracranial tumour growth through extracranial cDC1-mediated priming and expansion of CD8+ T cells which then home to intracranial tumours, by directly enhancing the activation of intracranial cDC1s, or a combination of both.

Dario Guglietta, Alca Revalova, Fiona R. James et al. · Neuro-Oncology · 0 citations