Dario Trapani

Early termination of clinical trials enrolling patients with breast cancer: Reasons, determinants, and temporal patterns

Background The occurrence of clinical trial termination before planned completion (or “early termination” [ET]) remains poorly characterized in the breast cancer field. This study investigates the reasons, determinants, and temporal patterns of ET in breast cancer trials. Methods We conducted a cross-sectional study us...

Exploring the immunological effects of antibody-drug conjugates.

Electronic patient-reported outcomes platforms to shift from episodic to continuous oncology in breast cancer.

EPROs represent a shift from episodic, visit-based assessment to more continuous and responsive monitoring in breast cancer care, and their clinical value is strongest when integrated into care pathways with clearly defined responsibilities and actionable workflows.