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Author

Darrell J. Irvine

2 papers indexed here

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Aug 2026

Cryopreservation of cell-based therapies with enhanced cell viability and therapeutic efficacy.

Biobanking has played an important role in advancing cell therapy by enabling long-term preservation of cell function, facilitating product transport, and allowing flexibility in infusion scheduling. However, conventional cryopreservation methods rely on high concentrations of dimethyl sulfoxide (DMSO) and serum, which...

Amy H. Lee, Khanh T. M. Tran, Alexander Hostetler et al. · 0 citations
Open access Aug 2026

Protective pan-betacoronavirus neutralizing antibodies by vaccination

The continued emergence of betacoronaviruses underscores the urgent need for vaccines that provide broadly protective immunity. Here, we present an epitope-focused vaccine strategy targeting the conserved S2 stem-helix region of the spike fusion machinery, a broadly neutralizing antibody-(bnAb) epitope shared across be...

Panpan Zhou, Ziqi Feng, Wan-ting He et al. · 0 citations

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