CRISPR-Cas9 as a Curative Frontier: Precision Editing Strategies for Sickle Cell Disease
Sickle cell anemia (SCA) is an inherited hematological disorder caused by the polymerization of defective hemoglobin that results in chronic hemolysis and recurrent vaso-occlusive crises. Conventional therapies, such as hydroxyurea administration and blood transfusions, have primarily focused on symptom management and...