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Author

David B. Sykes

1 paper indexed here

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Open access Aug 2026

Siglec-15 is a glyco-immune checkpoint in prostate cancer regulating immune evasion and metastasis

Prostate cancer is a leading cause of cancer-related mortality in men, and effective treatment options are limited for advanced and metastatic disease. The sialoglycan immune checkpoint Siglec-15 has emerged as a key mediator of tumour-associated immune suppression in several malignancies; however, its expression and f...

Nicoll Matthews, Fei-Er Zeng, Kirsty Hodgson et al. · 0 citations

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