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Author

David D. Fuller

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Open access Jul 2026

Antioxidant Upregulation Contributes to Improvements in Diaphragm Function Following Cervical Spinal Cord Injury and Hyperbaric Oxygen Therapy

Prevention of the HBO-induced upregulation of SOD1, SOD2 and GPX1 antioxidants reduces diaphragm-specific force production compared to the control, injured HBO-treated rats, providing evidence that the HBO-induced increase in SOD1, SOD2 and GPX1 antioxidant expression contributes, at least in part, to the therapeutic effect of HBO to preserve diaphragm function following cervical spinal cord injury.

C. C. Wendler, Prajwal P. Thakre, Kyle M. Deegan et al. · 0 citations