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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

Author

David H. Johnson

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2 papers indexed here

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Aug 2026

Membrane Remodeling by α-Synuclein Emerges from Complementary Contributions of Its Structured and Disordered Domains.

α-Synuclein (αSyn) remodels cellular membranes through interactions that involve both its structured, membrane-binding N-terminal domain (NTD) and intrinsically disordered C-terminal domain (CTD). While the amphipathic NTD helix is known to insert into lipid bilayers and generate curvature, the contribution of the acid...

David H. Johnson, Jia Shiuan Liow, O. Kou et al. · 0 citations
Open access Aug 2026

Membrane Phase, Charge, and Curvature Regulate α-Synuclein Binding Dynamics.

It is established that αSyn-membrane interactions are governed by a cooperative interplay between membrane phase, curvature, and charge and highlight the importance of resolving both thermodynamic and kinetic contributions to protein-membrane binding.

O. Kou, Cailyn M. Sakurai, Stephanie Y. Ramirez et al. · 0 citations

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