David Issadore

Ultrasound-assisted antifouling for continuous microfluidic manufacturing of RNA-LNP.

Microfluidic platforms produce RNA-loaded lipid nanoparticles (RNA-LNPs) with superior uniformity, encapsulation efficiency, and control over size compared to bulk methods, and unlike bulk approaches, their throughput can be scaled over orders of magnitude via parallelization without altering the formulation. Despite t...