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David R. Lightfoot

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Open access Sep 2026

Closing the Empirical Loop: Autonomous AI Agents Conduct End‐to‐end Research With Human Participants

ABSTRACT Artificial intelligence systems are transforming scientific discovery by accelerating specific research tasks, from protein structure prediction to materials design, yet remain confined to narrow domains requiring substantial human oversight. Exponential growth of scientific literature and increasing domain sp...

Gabrielle Wehr, Reuben Rideaux, Amaya J. Fox et al. · 0 citations

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