Author

David T. Evans

2 papers indexed here

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Open access Sep 2026

Vpu protects HIV-infected cells from antibody-dependent cellular phagocytosis by counteracting tetherin.

Tetherin is an interferon-inducible transmembrane protein that inhibits the detachment of enveloped viruses from infected cells. HIV-1 Vpu counteracts this restriction by removing tetherin from sites of virus release. Accordingly, Vpu mutations that disrupt tetherin antagonism increase Env accumulation on the surface o...

Brian J. Snow, Nida K. Keles, Ahmed Ali et al. · Cell Reports · 0 citations

Open access Aug 2026

Long-term depletion of KIR3DL01+ NK cells by adeno-associated viral-vectored antibody delivery alters chronic SIV infection

It is suggested that KIR3DL01+ NK cells contribute to the inhibition of SIV replication during chronic infection, and the feasibility of AAV-vectored antibody delivery for long-term, perhaps indefinite depletion of a lymphocyte subset in a nonhuman primate model is demonstrated.

Kjell Sandstrom, Grace N. Hagedorn, Sean C Robinson et al. · PLoS Pathogens · 0 citations