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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

David Villarroel-Campos

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Review Open access Oct 2026

Dual Roles of p53-Related Protein Kinase in Cytoskeletal Remodeling and Translational Control.

P53-related protein kinase (PRPK; TP53RK) is an evolutionarily conserved atypical kinase whose biology reveals an unexpected integration of translational control, cytoskeletal regulation, and cell-type-specific stress responses. As a core component of the TCTC complex (Threonyl-Carbamoyl Transferase Complex), PRPK part...

Emiliano Molina, David Villarroel-Campos, Manuel Muñoz et al. · 0 citations
Open access Sep 2026

Hyperactive KIF5A in Neurodegeneration.

The highly polarised morphology of neurons and the sheer length of their axons make transport of cargoes throughout the cell a formidable task. Decades of evidence obtained from genetic studies on patients and animal models highlight deficits in axonal transport as a recurrent cause, or early contributing factor, in a...

David Villarroel-Campos, J. N. Sleigh · 0 citations
Open access Jul 2026

The neuropathy-causing GARS1ΔETAQ mutation drives pathology in subsets of motor and sensory neurons in mice

Together, these experiments show that GarsΔETAQ/+ mice display robust and selective peripheral nerve pathology that manifests in a general distal-to-proximal fashion, priming this CMT2D allele for testing treatments and evaluating mechanisms underlying peripheral nerve vulnerability.

R. Simkin, A. Paulo-Ramos, Qiuhan Lang et al. · 0 citations

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