Isoprenoid Binding and Substrate Channeling in Drimenol Synthase, a Bifunctional Class II Terpene Cyclase-Phosphatase
More than one thousand bifunctional terpene synthases combining prenyltransferase and terpene cyclase activities have been identified in bacteria and fungi, but only a handful of enzymes have been identified that combine terpene cyclase activity with a downstream processing activity. Drimenol synthase from the marine b...