Open access
Aug 2026
Machine learning quantifies immuno-virological interactions: a TRIPOD+AI compliant prediction model for HIV-1 salvage therapy outcomes
Background The management of multidrug-resistant HIV-1 in patients experiencing virologic failure remains a critical clinical challenge. Traditional linear scoring systems often fail to adequately capture the complex evolutionary dynamics between the virus, host immunity, and antiretroviral regimens. This study aims to...
De-Fu Yuan, Yang-Yang Liu, Shan-Shan Liu et al.
· Frontiers in Immunology · 0 citations