Sep 2026
A novel chimeric antimicrobial peptide B5PL dual-targets bacterial cell membrane and neutrophils to combat multidrug-resistant bacterial infections.
A novel chimeric antimicrobial peptide B5PL is designed by fusing a truncated bovine β-defensin 5 (B5) domain with a PL-5 derivative peptide (PL) to exert direct-indirect antibacterial activities and remodel immune homeostasis against MDR bacterial infections.
Ren-Ling Wang, Yun Yang, Yu-Ping Chen et al.
· Bioorganic chemistry (Print) · 0 citations