Author

De-Min Cheng

2 papers indexed here

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Oct 2026

p62-Keap1-Nrf2 positive feedback loop protects against inorganic arsenic-induced senescence and EMT in alveolar type II cells.

Inorganic arsenic (As) exposure is known to induce pulmonary fibrosis, yet the underlying mechanisms remain incompletely understood. This study investigated the crosstalk between sequestosome 1 (SQSTM1/p62) and nuclear factor erythroid 2-related factor 2 (Nrf2) in regulating cellular senescence and epithelial-mesenchym...

Xin-Yang Guo, Xin-Yu Ma, Li-Yi Qin et al. · Cellular Signalling · 0 citations

Review Sep 2026

Neutrophil extracellular traps (NETs) and pulmonary fibrosis: Mechanisms and implications.

Pulmonary fibrosis is a fatal interstitial lung disease characterized by excessive fibroblast proliferation and aberrant deposition of extracellular matrix (ECM), ultimately leading to structural lung destruction and respiratory failure. Neutrophils, as key effector cells of innate immunity, have been increasingly reco...

Zu-Ming Chen, Jin-Yu Tang, Zi-Han Wang et al. · International Immunopharmaco... · 0 citations