Author

Debashis Ghosh

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Open access Sep 2026

ShadoNet: A Cell Detection and Classification Framework for Ki-67 Pathology Images.

MOTIVATION Accurate detection and classification of individual cells are essential for quantitative histopathology. In Ki-67-based tumor grading, the clinically relevant index is calculated from immunopositive and immunonegative tumor cells, while non-tumor cells should be excluded. This is challenging because Ki-67-st...

Mahsa Ghasemi, Fuyong Xing, Toby C. Cornish et al. · Bioinformatics · 0 citations

Open access Aug 2026

Nonparametric kernel-based detection of spatially variable genes with adaptive shrinkage and scalable multi-sample inference

CytoKspace is introduced, a nonparametric framework that combines a sparse exponential kernel constructed from nearest-neighbor graphs with a quadratic-form test statistic and adaptive permutation testing that demonstrates competitive sensitivity, well-calibrated false positive rates, and practical computational requir...

Tusharkanti Ghosh, Debashis Ghosh · bioRxiv · 0 citations