Low-Cost Nucleic-Acid-Based Radial Flow Assay for the Detection of GSTP1 Promoter DNA Methylation in Prostate Cancer.
A nucleic acid-based radial flow assay that enables visual and pattern-based detection of gene-specific DNA methylation using gold nanoparticle (AuNP)-conjugated oligonucleotide probes and provides a label-free and conversion-free analytical strategy for detection of methylation-protected GSTP1 DNA using minimal instru...