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Author

Deborah T. Hung

2 papers indexed here

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Open access Aug 2026

Mapping Essential Genes in Klebsiella pneumoniae Using Transposon-Insertion Sequencing (Tn-seq)

Klebsiella pneumoniae is a common cause of sepsis in adults and children. Given the emergence of multidrug-resistant isolates, there is an urgent need to develop novel therapeutic strategies. Essential bacterial genes and their products, which are critical to survival and replication, represent intrinsic vulnerab...

C. Wijers, J. Bagnall, Deborah T. Hung · 0 citations
Open access Jul 2026

A multimodal atlas of COVID-19 severity identifies hallmarks of dysregulated immunity 2258066

The alpha-variant wave of the COVID-19 pandemic provided a unique opportunity to study, at single-cell resolution, how near-universal exposure to the same pathogen can lead to either effective or dysfunctional immune responses in humans. We analyzed 2.5 million circulating immune cells from 428 patients ac...

Kamil Slowikowski, Pritha Sen, C. Cosgriff et al. · 0 citations

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