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Dechen Jiang

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Open access Aug 2026

A Metabolomics-Based Strategy for Identifying Endogenous Inhibitors of IAPP Aggregation

The identification of HPA as a potential endogenous inhibitor of IAPP aggregation provides new chemical insight into the relationship between metabolic dysregulation and amyloidogenesis and highlights endogenous metabolites as a valuable source of potential therapeutic lead compounds.

Dandan Xia, L. Gu, Lei Yang et al. · 0 citations