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Author

Deepak L. Bhatt

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Open access Oct 2026

Outcomes in patients with diabetes, atherosclerotic cardiovascular disease, and heart failure treated with tirzepatide or dulaglutide: SURPASS-CVOT analysis.

AIMS The impact of tirzepatide and dulaglutide on major adverse cardiovascular events (MACE) and heart failure (HF) outcomes according to HF status is unknown. METHODS AND RESULTS Patients with type 2 diabetes (T2D) and atherosclerotic cardiovascular disease were treated with tirzepatide up to 15 mg or dulaglutide 1....

S. J. Nicholls, I. Pavo, Deepak L. Bhatt et al. · 0 citations
Review Aug 2026

Comparative effectiveness of influenza vaccination dosing strategies for cardiovascular protection: a systematic review and network meta-analysis of randomised controlled trials.

BACKGROUND Influenza vaccination is recommended for cardiovascular secondary prevention, but the comparative effectiveness of different dose strategies remains incompletely characterised. METHODS We searched MEDLINE, Embase, and CENTRAL for randomised trials comparing high-dose (HD-IIV), double standard-dose, standar...

Joshua J. Hon, T. Aikawa, T. Biering-Sørensen et al. · 0 citations
Open access Aug 2026

Serial high-sensitivity troponin-T and risk of heart failure in individuals with suspected acute coronary syndrome.

AIMS To investigate the association between serial high-sensitivity cardiac troponin-T (hs-TnT) concentrations and subsequent heart failure in individuals presenting with suspected acute coronary syndrome (ACS). METHODS AND RESULTS Utilizing Danish nationwide registries, we identified individuals without known heart...

Philip Ahle Erichsen, Majid Afzal, Christina Byrne et al. · 1 citation
Open access Aug 2026

Incidence of Dementia in Older Adults Hospitalized With Acute Coronary Syndrome

Background Cognitive decline has been reported after coronary artery revascularization, but whether it reflects procedure-specific effects or the burden of underlying vascular disease remains uncertain. Objectives To determine whether incident dementia risk differs according to coronary revascularization strategy among...

Ashok Krishnaswami, Amanda Jain, Paola Gilsanz et al. · 0 citations
Open access Sep 2026

Persistent C-reactive protein elevation and incident heart failure in adults at increased cardiovascular risk: A multinational electronic health record study.

BACKGROUND Systemic inflammation has been associated with heart failure (HF) development. C-reactive protein (CRP) is a sensitive marker of inflammation, but its prognostic association with incident HF remains incompletely defined. We explored whether persistent CRP elevation was associated with incident HF among adult...

M. Busti, L. Monzo, T. Rastogi et al. · 1 citation
Open access Sep 2026

Five-Year Follow-Up of Transcatheter Aortic Valve Replacement With Self-Expanding Intra-Annular Versus Commercially Available Valves.

In patients at high or extreme surgical risk, TAVR with the self-expanding intra-annular transcatheter heart valve had similar 5-year overall survival, stroke rates, and valve function compared with commercially available valves.

Raj R. Makkar, Wen Cheng, Ron Waksman et al. · 0 citations
Sep 2026

Mitral Regurgitation and Severe Aortic Stenosis: Clinical Characteristics, Prognostic Impact, and Response to TAVR: Insights From Egnite Data.

Patients with concurrent MR and AS exhibit substantially higher mortality yet have high rates of undertreatment throughout the duration of follow-up, and TAVR alone significantly improves MR in most patients.

Benjamin E. Peterson, Philippe Généreaux, Pinak B. Shah et al. · 0 citations
Review Jul 2026

Refining the Role of Beta-Blockers in Cardiovascular Medicine.

This review highlights well established indications, such as chronic heart failure with reduced ejection fraction and angina, while also examining recent studies that have questioned routine use in certain scenarios.

B. Sperry, Mohammad Abdel Jawad, Deepak L. Bhatt et al. · 0 citations

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