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Author

Deepan Raji

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Open access Sep 2026

Edaravone as an antioxidant adjuvant to attenuate clozapine toxicity in vitro.

Despite being the gold-standard therapy for treatment-resistant schizophrenia, clozapine use remains constrained by the risk of rare but serious adverse drug reactions, including severe neutropenia and agranulocytosis. Neutrophil myeloperoxidase (MPO)-mediated bioactivation of clozapine to reactive metabolites has long...

Dinesh Babu, Thom H. Le, Huan Liu et al. · 1 citation

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