Deniz Yildirim

Immobilized Wild-Type and Mutant L‑Alanine Dehydrogenase from Thermus thermophilus Coupled with Formate Dehydrogenase for Asymmetric Synthesis of Noncanonical Amino Acids

The asymmetric synthesis of noncanonical amino acids (ncAAs) is of increasing interest due to their importance as precursors for pharmaceuticals, enzyme inhibitors, and functional peptide building blocks. In this study, wild-type and Tyr92Ser mutant l-alanine dehydrogenases from Thermus thermophilus (TtAlaDH) (WT and M...