Open access
Oct 2026
A chemigenetic fluorescence lifetime-based biosensor for imaging of ERK activity
Extracellular signal-regulated kinase (ERK) governs many cellular processes, and its spatiotemporal activity dynamics are important for downstream signaling specificity. Existing fluorescent ERK activity biosensors, however, fall short in enabling spectrally multiplexed, spatially resolved, or deep tissue measurements....
Elias Dressler, Rohan S. Eapen, Dennis Pellanda et al.
· bioRxiv · 0 citations