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Deyin Guo

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Open access Sep 2026

An Engineered HR1‐Stem Helix‐HR2 Trimeric Platform for Developing Broad‐Spectrum Coronavirus Vaccines

RHS is established as a generalizable strategy for overcoming viral immune evasion and advancing next‐generation vaccine design, and is readily adaptable to antigens from SARS‐CoV and MERS‐CoV, underscoring its versatility for pan‐coronavirus vaccine development.

Xi-Kui Sun, Junhao Fan, Xiaolu Xie et al. · 0 citations
Open access Aug 2026

SARS-CoV-2 3CLpro inhibits the replication of influenza viruses through the cleavage of NP and PA

The data uncover a direct, enzyme-based mechanism by which SARS-CoV-2 can suppress influenza virus replication during coinfection and provide a molecular explanation for the sharp, global decline in influenza activity observed during the COVID-19 pandemic.

Liubing Du, Xiaoyu Cai, Zi-Tao Peng et al. · 0 citations

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