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Open access Aug 2026

TRIM21 suppresses uterine corpus endometrial carcinoma progression by promoting K48 -linked ubiquitination and degradation of SOAT1

Background Uterine corpus endometrial carcinoma (UCEC) is one of the most common gynecological malignancies, and its progression is closely associated with dysregulated protein homeostasis and metabolic reprogramming. TRIM21 is an E3 ubiquitin ligase implicated in tumor regulation, but its role in UCEC remains unclear....

Hongwei Chen, Di Cui · 0 citations

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