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Review Sep 2026

Metabolic reprogramming underlying EGFR-TKI resistance in lung cancer.

Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) have significantly improved the clinical efficacy in non-small cell lung cancer (NSCLC) patients with EGFR mutations. However, acquired resistance to EGFR-TKIs remains an unavoidable therapeutic bottleneck. The metabolic reprogramming underlying th...

Xiao-Long Huang, Tao Cheng, Fengkai Xu et al. · 0 citations

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